Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748768 | 0.90 | ELANE (0.36) | CNR1ACHECNR2ACSS2 | |
| SCHEMBL4140168 | 0.70 | ELANE (0.51) | — | |
| SCHEMBL12373963 | 0.67 | CNR1 (0.39) | CNR1ACHECNR2MAPK1ACSS2 | |
| SCHEMBL18113532 | 0.64 | CNR1 (0.36) | CNR1ACHECNR2MAPK1ACSS2 | |
| SCHEMBL19672028 | 0.64 | FGFR1 (0.33) | — | |
| SCHEMBL13854954 | 0.63 | KMT2A (0.38) | MAPK1 | |
| SCHEMBL16025626 | 0.63 | ELANE (0.37) | — | |
| SCHEMBL2280858 | 0.63 | CNR1 (0.35) | CNR1ACHECNR2MAPK1 | |
| SCHEMBL19671840 | 0.62 | ACSS2 (0.36) | ACSS2 | |
| SCHEMBL30084116 | 0.62 | PTGER1 (0.38) | CNR1ACHECNR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105500-A1 | COMPOUNDS THAT ARE ERK INHIBITORS | SCHERING CORPORATION (US) | 2009-08-27 | — | — | WO | disclosed |