Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358062 | 0.81 | TDP1 (0.66) | ATMTDP1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL3826534 | 0.80 | ATM (0.58) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| SCHEMBL6027916 | 0.79 | TDP1 (0.58) | ATMTDP1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL709403 | 0.79 | L3MBTL1 (0.68) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| Hydrochloric Acid SCHEMBL10405007 | 0.79 | ATM (0.56) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| SCHEMBL29503119 | 0.79 | L3MBTL1 (0.68) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| SCHEMBL9267070 | 0.79 | ATM (0.56) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| SCHEMBL6028190 | 0.78 | TDP1 (0.56) | ATMTDP1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL21530481 | 0.77 | CYP1A2 (0.49) | ATMTDP1L3MBTL1MAPK8MAPK9 | |
| SCHEMBL4685576 | 0.76 | TDP1 (0.55) | ATMTDP1L3MBTL1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197895-A1 | OXAZOLE-PYRROLE-PIPERAZINE ALPHA-HELIX MIMETIC | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197895-A1 | OXAZOLE-PYRROLE-PIPERAZINE ALPHA-HELIX MIMETIC | OXA1L, OCIAD1, OCIAD2 | ATM 4409/4885TDP1 3455/4885L3MBTL1 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.