Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753177 | 1.00 | RAB9A (0.68) | RAB9ANPC1LMNAHPGDMEN1 | |
| SCHEMBL13753172 | 0.82 | RAB9A (0.76) | RAB9ANPC1LMNAHPGDMEN1 | |
| SCHEMBL13761410 | 0.82 | RAB9A (0.76) | RAB9ANPC1LMNAHPGDMEN1 | |
| SCHEMBL13761411 | 0.82 | RAB9A (0.76) | RAB9ANPC1LMNAHPGDMEN1 | |
| SCHEMBL13753582 | 0.81 | KMT2A (0.58) | RAB9ANPC1LMNAHPGDMEN1 | |
| SCHEMBL13753171 | 0.81 | RAB9A (0.74) | RAB9ANPC1LMNAHPGDMEN1 | |
| SCHEMBL13753161 | 0.81 | RAB9A (0.74) | RAB9ANPC1LMNAHPGDMEN1 | |
| SCHEMBL13753162 | 0.81 | RAB9A (1.00) | RAB9ANPC1LMNAHPGDMEN1 | |
| SCHEMBL13753176 | 0.80 | RAB9A (0.74) | RAB9ANPC1LMNAHPGDMEN1 | |
| SCHEMBL13753166 | 0.80 | RAB9A (0.74) | RAB9ANPC1LMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |