Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720276 | 0.86 | GAA (1.00) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL13753522 | 0.85 | GAA (0.78) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL13761470 | 0.85 | GAA (0.78) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL13753525 | 0.84 | GAA (0.71) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL20370207 | 0.84 | GAA (0.76) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL13753550 | 0.84 | HPGD (0.76) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL12812547 | 0.83 | HPGD (0.75) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL2729249 | 0.83 | GAA (0.84) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL13753552 | 0.82 | GAA (0.59) | GAAHPGDCA12CA1CA2 | |
| SCHEMBL13908531 | 0.82 | GAA (0.68) | GAAHPGDCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |