SCHEMBL2729249

SCHEMBL2729249

CC1CCCCN1C(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.84
HPGD P15428 2/20 0.84
CA12 O43570 1/20 0.70
CA1 P00915 1/20 0.70
CA2 P00918 1/20 0.70
CA7 P43166 1/20 0.70
CA9 Q16790 1/20 0.70
CA14 Q9ULX7 1/20 0.70
LMNA P02545 1/20 0.63
ALDH1A1 P00352 2/20 0.60
NAMPT P43490 2/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
MAPT P10636 1/20 0.55
HSD11B1 P28845 3/20 0.52
MAPK1 P28482 1/20 0.51
GRM5 P41594 1/20 0.50
HTT P42858 1/20 0.50
HRH3 Q9Y5N1 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10720276 0.92 GAA (1.00) GAAHPGDCA12CA1CA2
SCHEMBL788241 0.84 GAA (0.84) GAAHPGDCA12CA1CA2
SCHEMBL16254905 0.84 GAA (0.84) GAAHPGDCA12CA1CA2
SCHEMBL16254982 0.84 HPGD (0.84) GAAHPGDCA12CA1CA2
SCHEMBL1102309 0.84 HPGD (0.84) GAAHPGDCA12CA1CA2
SCHEMBL14645801 0.84 HPGD (0.84) GAAHPGDCA12CA1CA2
SCHEMBL6688685 0.84 HPGD (0.84) GAAHPGDCA12CA1CA2
SCHEMBL13753545 0.83 GAA (0.76) GAAHPGDCA12CA1CA2
SCHEMBL13761470 0.81 GAA (0.78) GAAHPGDCA12CA1CA2
SCHEMBL13753522 0.81 GAA (0.78) GAAHPGDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3898820-A1 POLYMERIC COMPOSITIONS WITH HIGH DIELECTRIC CONSTANT AND LOW DIELECTRIC LOSS Dupont Polymers, Incorporated (US) 2021-10-27 EP disclosed
WO-2020131212-A1 POLYMERIC COMPOSITIONS WITH HIGH DIELECTRIC CONSTANT AND LOW DIELECTRIC LOSS DUPONT POLYMERS, INCORPORATED (US) 2020-06-25 WO disclosed
EP-2479202-B1 THERMALLY-CONDUCTIVE ORGANIC ADDITIVE, RESIN COMPOSITION, AND CURED PRODUCT KANEKA CORP (JP) 2019-02-13 EP disclosed
US-9234095-B2 Thermally-conductive organic additive, resin composition, and cured product KANEKA CORPORATION (JP) 2016-01-12 US disclosed
US-20150025188-A1 THERMALLY-CONDUCTIVE ORGANIC ADDITIVE, RESIN COMPOSITION, AND CURED PRODUCT KANEKA CORPORATION (JP) 2015-01-22 US disclosed
EP-2632719-A2 COMPOSITE STRUCTURES HAVING IMPROVED HEAT AGING AND INTERLAYER BOND STRENGTH E.I. Du Pont De Nemours And Company (US) 2013-09-04 EP disclosed
EP-2479202-A1 THERMALLY-CONDUCTIVE ORGANIC ADDITIVE, RESIN COMPOSITION, AND CURED PRODUCT Kaneka Corporation (JP) 2012-07-25 EP disclosed
US-20120175549-A1 THERMALLY-CONDUCTIVE ORGANIC ADDITIVE, RESIN COMPOSITION, AND CURED PRODUCT KANEKA CORPORATION (JP) 2012-07-12 US disclosed
WO-2012058379-A2 COMPOSITE STRUCTURES HAVING IMPROVED HEAT AGING AND INTERLAYER BOND STRENGTH E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120175549-A1 THERMALLY-CONDUCTIVE ORGANIC ADDITIVE, RESIN COMPOSITION, AND CURED PRODUCT MEP1A, SEM1, COL1A1 GAA 2872/4885HPGD 4182/4885CA12 2417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.