Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RHOC | P08134 | 2/20 | 0.47 |
| ▸ | RHOA | P61586 | 2/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753509 | 0.92 | HPGD (0.56) | HPGDGAARHOCRHOAPDK2 | |
| SCHEMBL30009432 | 0.83 | HPGD (0.69) | HPGDGAAPDK2POLBCA12 | |
| SCHEMBL13753528 | 0.82 | HPGD (0.59) | HPGDGAAPDK2POLBCA12 | |
| SCHEMBL27424708 | 0.81 | HPGD (0.54) | HPGDGAAPDK2POLBCA12 | |
| SCHEMBL13753524 | 0.81 | GAA (0.69) | HPGDGAAPDK2CA12CA1 | |
| SCHEMBL13761333 | 0.79 | HPGD (0.51) | HPGDGAAPDK2POLBCA12 | |
| SCHEMBL31006695 | 0.77 | MEN1 (0.49) | HPGDGAAPDK2POLBCA12 | |
| SCHEMBL22054772 | 0.77 | GAA (0.59) | HPGDGAAPDK2USP2SMN1; SMN2 | |
| SCHEMBL21697075 | 0.77 | GAA (0.59) | HPGDGAAPDK2USP2SMN1; SMN2 | |
| SCHEMBL16254932 | 0.77 | GAA (0.77) | HPGDGAAPDK2POLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |