SCHEMBL13754332

SCHEMBL13754332

CC1=CCC(C(=O)N2CCOC3(CCN(Cc4cccc(CCO)c4)CC3)C2)S1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 20/20 0.48
CHRM3 P20309 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13754444 0.84 CHRM3 (0.38) CHRM2CHRM3
SCHEMBL2142503 0.78 CHRM2 (0.54) CHRM2CHRM3
SCHEMBL2141024 0.77 CHRM2 (0.49) CHRM2CHRM3
SCHEMBL13754449 0.77 ADRB2 (0.49) CHRM3
SCHEMBL13754316 0.77 ADRB2 (0.61) CHRM3
SCHEMBL2142878 0.76 CHRM2 (0.80) CHRM2CHRM3
SCHEMBL2140688 0.76 CHRM2 (0.54) CHRM2CHRM3
SCHEMBL2141565 0.76 CHRM2 (0.57) CHRM2CHRM3
SCHEMBL2138569 0.75 CHRM2 (0.51) CHRM2CHRM3
SCHEMBL2142017 0.75 CHRM2 (0.55) CHRM2CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009098448-A1 COMPOUNDS ASTRAZENECA AB (SE) 2009-08-13 WO disclosed