SCHEMBL1375441

SCHEMBL1375441

Sc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.Sc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.[MgH2]

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL601867 1.00 ALDH1A1 (0.31) ALDH1A1TSHRMEN1LMNAMAPT
SCHEMBL48512 0.95 ALDH1A1 (0.33) ALDH1A1TSHRMEN1LMNAMAPT
SCHEMBL6519472 0.91 ALDH1A1 (0.31) ALDH1A1TSHRMEN1LMNAMAPT
SCHEMBL602547 0.91 ALDH1A1 (0.31) ALDH1A1TSHRMEN1LMNAMAPT
SCHEMBL11077811 0.91 ALDH1A1 (0.31) ALDH1A1TSHRMEN1LMNAMAPT
SCHEMBL15561424 0.91 ALDH1A1 (0.31) ALDH1A1TSHRMEN1LMNAMAPT
SCHEMBL1951617 0.91 ALDH1A1 (0.31) ALDH1A1TSHRMEN1LMNAMAPT
Ammonia Solution, Strong SCHEMBL1265757 0.91 ALDH1A1 (0.31) ALDH1A1TSHRMEN1LMNAMAPT
SCHEMBL11120337 0.91 ALDH1A1 (0.31) ALDH1A1TSHRMEN1LMNAMAPT
SCHEMBL11124925 0.91 ALDH1A1 (0.31) ALDH1A1TSHRMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8454455-B2 Multilayer golf ball containing at least three core layers, at least one intermediate barrier layer, and at least one cover layer ACUSHNET COMPANY (US) 2013-06-04 US disclosed
US-20120295737-A1 MULTILAYER GOLF BALL CONTAINING AT LEAST THREE CORE LAYERS, AT LEAST ONE INTERMEDIATE BARRIER LAYER, AND AT LEAST ONE COVER LAYER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2012-11-22 US disclosed
US-8298099-B2 Multi-layer core golf ball having thermoset rubber cover ACUSHNET COMPANY (US) 2012-10-30 US disclosed
US-8251839-B2 Multilayer golf ball containing at least three core layers, at least one intermediate barrier layer, and at least one cover layer ACUSHNET COMPANY (US) 2012-08-28 US disclosed
US-20110287860-A1 MULTI-LAYER CORE GOLF BALL HAVING THERMOSET RUBBER COVER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2011-11-24 US disclosed
US-8007374-B2 Multi-layer core golf ball having thermoset rubber cover ACUSHNET COMPANY (US) 2011-08-30 US disclosed
US-20110190076-A1 MULTILAYER GOLF BALL CONTAINING AT LEAST THREE CORE LAYERS, AT LEAST ONE INTERMEDIATE BARRIER LAYER, AND AT LEAST ONE COVER LAYER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2011-08-04 US disclosed
US-7951015-B2 Multilayer golf ball containing at least three core layers, at least one intermediate barrier layer, and at least one cover layer ACUSHNET COMPANY (US) 2011-05-31 US disclosed
US-7654918-B2 Multi-layer core golf ball having thermoset rubber cover ACUSHNET COMPANY (US) 2010-02-02 US disclosed
US-7635312-B2 Multi-layer golf ball having velocity gradient from faster center to slower cover ACUSHNET COMPANY (US) 2009-12-22 US disclosed
US-20080171617-A1 MULTI-LAYER GOLF BALL HAVING VELOCITY GRADIENT FROM FASTER CENTER TO SLOWER COVER ACUSHNET COMPANY 2008-07-17 US disclosed
US-20080096693-A1 Multi-Layer Golf Ball having Velocity Gradient from Slower Center to Faster Cover ACUSHNET COMPANY 2008-04-24 US disclosed
US-7331878-B2 Multi-layer golf ball having velocity gradient from slower center to faster cover ACUSHNET COMPANY (US) 2008-02-19 US disclosed
US-7300364-B2 Multi-layer golf ball having velocity gradient from faster center to slower cover ACUSHNET COMPANY (US) 2007-11-27 US disclosed
US-20070129172-A1 MULTILAYER GOLF BALL CONTAINING AT LEAST THREE CORE LAYERS, AT LEAST ONE INTERMEDIATE BARRIER LAYER, AND AT LEAST ONE COVER LAYER JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2007-06-07 US disclosed
US-20070093318-A1 Multi-Layer Core Golf Ball Having Thermoset Rubber Cover JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2007-04-26 US disclosed
US-20060211518-A1 Multi-Layer Golf Balls Comprising Ionomers with a Percent Neutralization Gradient ACUSHNET COMPANY 2006-09-21 US disclosed
US-20060189413-A1 Multi-layer golf ball having velocity gradient from faster center to slower cover JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-08-24 US disclosed
US-20050187347-A1 Golf ball composition having substantially no ZDA coagent ACUSHNET COMPANY 2005-08-25 US disclosed
US-20050176523-A1 Multi-layer golf ball having velocity gradient from slower center to faster cover JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-08-11 US disclosed