Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369663 | 0.83 | HDAC3 (0.48) | CA2PPARGHDAC3HDAC1HDAC2 | |
| SCHEMBL15521418 | 0.81 | FFAR1 (0.53) | CA2LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL17585416 | 0.81 | HDAC3 (0.43) | CA2PPARGHDAC3HDAC1HDAC2 | |
| SCHEMBL14189703 | 0.81 | HDAC3 (0.45) | CA2PPARGGAAHDAC3HDAC1 | |
| SCHEMBL14551994 | 0.79 | CYP4F2 (0.53) | LMNAGAAHDAC3HDAC1HDAC2 | |
| SCHEMBL21087169 | 0.79 | HDAC8 (0.45) | CA2PPARGHDAC3HDAC1HDAC2 | |
| SCHEMBL21118382 | 0.79 | HDAC3 (0.45) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL25137175 | 0.78 | HDAC3 (0.54) | PPARGLMNAHTTHDAC3HDAC1 | |
| SCHEMBL31096813 | 0.77 | PPARG (0.46) | CA2CAMK2APPARGLMNAGAA | |
| Acetic Acid SCHEMBL29114915 | 0.77 | HDAC3 (0.46) | AKR1B1LMNAGAAHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105746-A2 | TRIAZOLES AND PROCESSES FOR PRODUCING THE SAME | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-08-27 | — | — | WO | disclosed |