Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.66 |
| ▸ | PGR | P06401 | 11/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474764 | 0.87 | NR3C1 (0.61) | NR3C1NR3C2PGRCYP2A13 | |
| SCHEMBL4469152 | 0.87 | NR3C1 (0.61) | NR3C1NR3C2PGRCYP2A13 | |
| SCHEMBL4468861 | 0.86 | NR3C1 (0.69) | NR3C1NR3C2PGR | |
| SCHEMBL4469118 | 0.84 | NR3C1 (0.66) | NR3C1NR3C2PGR | |
| SCHEMBL4472464 | 0.83 | NR3C1 (0.70) | NR3C1NR3C2PGR | |
| SCHEMBL4478157 | 0.80 | NR3C1 (0.80) | NR3C1NR3C2PGR | |
| SCHEMBL4477613 | 0.80 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL291599 | 0.78 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL292589 | 0.78 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL292268 | 0.77 | NR3C1 (1.00) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |