Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13754578 | 0.95 | ADRB2 (0.54) | ADRB2CHRM3 | |
| SCHEMBL13754674 | 0.95 | ADRB2 (0.53) | ADRB2CHRM3ADRA1DCA1CA2 | |
| SCHEMBL13754626 | 0.94 | ADRB2 (0.55) | ADRB2CHRM3CA1CA2HSD17B2 | |
| SCHEMBL13754576 | 0.93 | ADRB2 (0.71) | ADRB2CHRM3 | |
| SCHEMBL13754573 | 0.91 | ADRB2 (0.61) | ADRB2CHRM3 | |
| SCHEMBL13754553 | 0.90 | ADRB2 (0.51) | ADRB2CHRM3CA1CA2 | |
| SCHEMBL13754624 | 0.90 | ADRB2 (0.64) | ADRB2 | |
| SCHEMBL14429837 | 0.90 | ADRB2 (0.52) | ADRB2CHRM3 | |
| SCHEMBL14429835 | 0.89 | ADRB2 (0.58) | ADRB2CHRM3 | |
| SCHEMBL13590819 | 0.89 | ADRB2 (0.56) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624868-B9 | \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS | PFIZER LTD (GB) | 2009-08-12 | — | — | EP | disclosed |
| US-7268147-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2007-09-11 | — | — | US | disclosed |