Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429833 | 0.93 | ADRB2 (0.58) | ADRB2 | |
| SCHEMBL13754579 | 0.86 | ADRB2 (0.52) | ADRB2 | |
| SCHEMBL4260998 | 0.86 | ADRB2 (0.66) | ADRB2 | |
| SCHEMBL4261007 | 0.86 | ADRB2 (0.66) | ADRB2 | |
| SCHEMBL4255165 | 0.86 | ADRB2 (0.51) | ADRB2LMNATP53MEN1KMT2A | |
| SCHEMBL4255168 | 0.86 | ADRB2 (0.51) | ADRB2LMNATP53MEN1KMT2A | |
| SCHEMBL13754558 | 0.86 | ADRB2 (0.50) | ADRB2 | |
| SCHEMBL13754624 | 0.84 | ADRB2 (0.64) | ADRB2 | |
| SCHEMBL14430026 | 0.84 | ADRB2 (0.47) | ADRB2 | |
| SCHEMBL14429290 | 0.83 | ADRB2 (0.51) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624868-B9 | \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS | PFIZER LTD (GB) | 2009-08-12 | — | — | EP | disclosed |
| EP-1624868-B1 | \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS | PFIZER LTD (GB) | 2008-11-12 | — | — | EP | disclosed |
| US-7268147-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2007-09-11 | — | — | US | disclosed |