⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515442 | 0.70 | — | — | |
| Formic Acid SCHEMBL27874497 | 0.64 | — | — | |
| Formic Acid SCHEMBL27806685 | 0.64 | — | — | |
| Formic Acid SCHEMBL27595292 | 0.61 | RPS6KA3 (0.40) | — | |
| SCHEMBL28165370 | 0.61 | — | — | |
| Thiazole-5-Carbaldehyde SCHEMBL194323 | 0.58 | — | — | |
| Thiazole-5-Carbaldehyde SCHEMBL1316528 | 0.58 | PIM1 (0.42) | — | |
| SCHEMBL17099921 | 0.58 | ALDH1A1 (0.48) | — | |
| SCHEMBL27362475 | 0.57 | — | — | |
| SCHEMBL30957 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555594-A | Substituted azaheterocycles as TRMP8 modulators | 奇华顿股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-103214475-B | One class contains 4-methyl isophthalic acid, α-(replacement) hydroxyamide derivatives of 2,3-thiadiazoles and its production and use | NANKAI UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-103012391-B | Pyrimidine derivatives containing 1,2,3-thiadiazole, and preparation method and application thereof | ANIMAL & PLANT & FOOD INSPECTION CT TIANJIN ENTRY EXIT INSPECTION & QUARANTINE BUREAU | 2015-04-22 | — | — | CN | claimed |
| CN-104447617-A | Synthesis and application of nitro arylideneamino guanidine compounds containing 1, 2, 3-thiadiazole | UNIV NANKAI | 2015-03-25 | — | — | CN | claimed |
| CN-103012392-B | Pyridine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | UNIV NANKAI | 2015-03-04 | — | — | CN | claimed |
| CN-102417505-B | Tetrazole compounds containing methyl-1,2,3-thiadiazole as well as preparation methods and application thereof | UNIV NANKAI | 2014-07-09 | — | — | CN | claimed |
| CN-102633744-B | 3-(4-methyl-1, 2, 3-thiadiazole-5-yl)-1, 5-diketone derivatives as well as preparation method and application thereof | UNIV NANKAI | 2014-06-18 | — | — | CN | claimed |
| CN-103214475-A | Alpha-(substituted)oxyamide derivatives containing 4-methyl-1,2,3-thiadiazole and preparation methods and application thereof | UNIV NANKAI | 2013-07-24 | — | — | CN | claimed |
| CN-103012392-A | Pyridine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | UNIV NANKAI | 2013-04-03 | — | — | CN | claimed |
| CN-103012391-A | Pyrimidine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | ANIMAL PLANT AND FOOD TESTING CT OF TIANJIN ENTRY EXIT INSPECTION AND QUARANTIME BUREAU | 2013-04-03 | — | — | CN | claimed |
| CN-102816134-A | 1,2,3-thiadiazole-containing sulfilimine (sulfonimine) compounds and their preparation method and use | UNIV NANKAI | 2012-12-12 | — | — | CN | claimed |
| CN-102417505-A | Tetrazole compounds containing methyl-1,2,3-thiadiazole as well as preparation methods and application thereof | UNIV NANKAI | 2012-04-18 | — | — | CN | claimed |
| CN-1678298-A | Use of an alpha2delta ligand such as gabapentin or pregabalin for treating ttention deficit hyperactivity disorder | WARNER LAMBERT CO (US) | 2005-10-05 | — | — | CN | claimed |
| CN-1625393-A | Alpha 2 delta ligands to treat tinnitus | WARNER LAMBERT CO (US) | 2005-06-08 | — | — | CN | claimed |
| EP-0824317-B1 | AN AGRICULTURAL AND HORTICULTURAL DISEASE CONTROLLER AND A METHOD FOR CONTROLLING THE DISEASES | NIHON NOHYAKU CO LTD (JP) | 2004-10-13 | — | — | EP | claimed |
| US-6521649-B1 | 1,2,3-thiadiazole derivatives; expanding spectrum of controllable diseases and period of time when effective applications are possible; reducing dosage | NIHON NOHAYKU CO., LTD. (JP) | 2003-02-18 | — | — | US | claimed |
| CN-1279673-A | ((Cyclo) alkyl substituted-.gamma.-aminobutyric acid derivatives (=GABA analogurs), their preparation and their use in the treatment of neurolog disorders | WARNER LAMBERT CO (US) | 2001-01-10 | — | — | CN | claimed |
| EP-0824317-A2 | AN AGRICULTURAL AND HORTICULTURAL DISEASE CONTROLLER AND A METHOD FOR CONTROLLING THE DISEASES | Nihon Nohyaku Co., Ltd. (JP) | 1998-02-25 | — | — | EP | claimed |
| WO-1996029871-A2 | AN AGRICULTURAL AND HORTICULTURAL DISEASE CONTROLLER AND A METHOD FOR CONTROLLING THE DISEASES | NIHON NOHYAKU CO., LTD. (JP) | 1996-10-03 | — | — | WO | claimed |
| US-20240238183-A1 | COMPOSITIONS THAT ENHANCE THE COOLING EFFECT | FIRMENICH INCORPORATED (US) | 2024-07-18 | — | — | US | disclosed |
| CN-117479843-A | Composition for enhancing cooling effect | 弗门尼舍公司 | 2024-01-30 | — | — | CN | disclosed |
| US-20230331724-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-10-19 | — | — | US | disclosed |
| US-11731971-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-08-22 | — | — | US | disclosed |
| US-20230066268-A1 | INDAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPES VIRUSES | MERCK SHARP & DOHME LLC (US) | 2023-03-02 | — | — | US | disclosed |
| EP-4076444-A1 | INDAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPES VIRUSES | Merck Sharp & Dohme LLC (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-114555594-A | Substituted azaheterocycles as TRMP8 modulators | 奇华顿股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-20210371419-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| US-11117896-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| WO-2021126804-A1 | INDAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPES VIRUSES | MERCK SHARP & DOHME CORP. (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-107406437-B | Process for preparing 1,2, 4-oxadiazole derivatives | AGC株式会社 | 2021-01-05 | — | — | CN | disclosed |
| US-20200048253-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-13 | — | — | US | disclosed |
| US-10556905-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-11 | — | — | US | disclosed |
| WO-2020016434-A1 | CYCLIC INHIBITORS OF HEPATITIS B VIRUS | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2020-01-23 | — | — | WO | disclosed |
| EP-3597653-A1 | CYCLIC INHIBITORS OF HEPATITIS B VIRUS | IRBM S.P.A. (IT) | 2020-01-22 | — | — | EP | disclosed |
| EP-2857401-B1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |
| CN-106995420-B | A kind of thiadiazoles oxime ether methoxy base acrylate derivative and its preparation method and application | 南开大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-109651293-A | A kind of diazosulfide phenylacetonitrile derivative and its preparation method and application | 湖州师范学院 | 2019-04-19 | — | — | CN | disclosed |
| US-20180258089-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-09-13 | — | — | US | disclosed |
| US-10023573-B2 | Beta-lactamase inhibitor and process for preparing the same | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-9938258-B2 | Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof | Karyopharm Therapeutics Inc. (US) | 2018-04-10 | — | — | US | disclosed |
| US-9938258-B2 | Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof | Karyopharm Therapeutics Inc. (US) | 2018-04-10 | — | — | US | disclosed |
| CN-104447617-B | The synthesis of nitro contracting amino guanidine compound of the one kind containing 1,2,3 thiadiazoles and purposes | 南开大学 | 2017-12-05 | — | — | CN | disclosed |
| CN-107406437-A | The method for preparing 1,2,4 oxadiazole derivatives | 旭硝子株式会社 | 2017-11-28 | — | — | CN | disclosed |
| CN-105439979-B | Benzoyl hydazone derivative containing 1,2,3 thiadiazoles and preparation method and application | 中国农业大学 | 2017-11-10 | — | — | CN | disclosed |
| US-20170233393-A1 | BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-08-17 | — | — | US | disclosed |
| CN-106995420-A | One class thiadiazoles oxime ether methoxy base acrylate derivative and its production and use | 南开大学 | 2017-08-01 | — | — | CN | disclosed |
| US-9708320-B2 | β-lactamase inhibitor and process for preparing the same | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-07-18 | — | — | US | disclosed |
| CN-104583197-B | New bicyclicpyridine derivatives | 霍夫曼-拉罗奇有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-104755460-B | N-acylhydrazone derivatives for selective T cell inhibitor and anti-lymphoid malignancy drug | 株式会社钟根堂 | 2017-05-10 | — | — | CN | disclosed |
| US-20160221994-A1 | Substituted 2,3-Dihydrobenzofuranyl Compounds And Uses Thereof | Karyopharm Therapeutics Inc. | 2016-08-04 | — | — | US | disclosed |
| US-20160221994-A1 | Substituted 2,3-Dihydrobenzofuranyl Compounds And Uses Thereof | Karyopharm Therapeutics Inc. | 2016-08-04 | — | — | US | disclosed |
| CN-105439979-A | 1,2,3-thiadiazole-containing benzoyl hydrazone derivative as well as preparation method and application thereof | UNIV CHINA AGRICULTURAL | 2016-03-30 | — | — | CN | disclosed |
| US-20160024090-A1 | BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| CN-103214475-B | One class contains 4-methyl isophthalic acid, α-(replacement) hydroxyamide derivatives of 2,3-thiadiazoles and its production and use | NANKAI UNIVERSITY (CN) | 2016-01-20 | — | — | CN | disclosed |
| US-9181250-B2 | Beta-lactamase inhibitor and process for preparing the same | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| CN-104755460-A | N-acylhydrazone derivatives for selective T cell inhibitor and anti-lymphoid malignancy drug | CHONG KUN DANG PHARM CORP | 2015-07-01 | — | — | CN | disclosed |
| US-20150141401-A1 | NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2015-05-21 | — | — | US | disclosed |
| CN-103012391-B | Pyrimidine derivatives containing 1,2,3-thiadiazole, and preparation method and application thereof | ANIMAL & PLANT & FOOD INSPECTION CT TIANJIN ENTRY EXIT INSPECTION & QUARANTINE BUREAU | 2015-04-22 | — | — | CN | disclosed |
| EP-2857401-A1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | Meiji Seika Pharma Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |
| CN-104447617-A | Synthesis and application of nitro arylideneamino guanidine compounds containing 1, 2, 3-thiadiazole | UNIV NANKAI | 2015-03-25 | — | — | CN | disclosed |
| CN-103012392-B | Pyridine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | UNIV NANKAI | 2015-03-04 | — | — | CN | disclosed |
| CN-102417505-B | Tetrazole compounds containing methyl-1,2,3-thiadiazole as well as preparation methods and application thereof | UNIV NANKAI | 2014-07-09 | — | — | CN | disclosed |
| CN-102816134-B | 1,2,3-thiadiazole-containing sulfilimine (sulfonimine) compounds and their preparation method and use | UNIV NANKAI | 2014-07-02 | — | — | CN | disclosed |
| CN-102633744-B | 3-(4-methyl-1, 2, 3-thiadiazole-5-yl)-1, 5-diketone derivatives as well as preparation method and application thereof | UNIV NANKAI | 2014-06-18 | — | — | CN | disclosed |
| WO-2014085607-A1 | SUBSTITUTED 2,3-DIHYDROBENZOFURANYL COMPOUNDS AND USES THEREOF | Karyopharm Therapeutics Inc. (US) | 2014-06-05 | — | — | WO | disclosed |
| CN-101878219-B | Imidazothiadiazoles for use as protein kinase inhibitors | CT NAC DE INVESTIGACIONES ONCO | 2014-04-02 | — | — | CN | disclosed |
| US-8648075-B2 | Substituted pyrido[2,3-b]pyrazines and an agrochemical composition thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| EP-2394995-B1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-01-15 | — | — | EP | disclosed |
| CN-103214475-A | Alpha-(substituted)oxyamide derivatives containing 4-methyl-1,2,3-thiadiazole and preparation methods and application thereof | UNIV NANKAI | 2013-07-24 | — | — | CN | disclosed |
| US-20130137577-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
| CN-103012392-A | Pyridine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | UNIV NANKAI | 2013-04-03 | — | — | CN | disclosed |
| CN-103012391-A | Pyrimidine derivatives containing 1.2,3-thiadiazole, and preparation method and application thereof | ANIMAL PLANT AND FOOD TESTING CT OF TIANJIN ENTRY EXIT INSPECTION AND QUARANTIME BUREAU | 2013-04-03 | — | — | CN | disclosed |
| US-8389523-B2 | Substituted quinoxaline and an agrochemical composition thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-03-05 | — | — | US | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| CN-101687876-B | Amino-heterocyclic compounds | PFIZER | 2012-12-12 | — | — | CN | disclosed |
| CN-102816134-A | 1,2,3-thiadiazole-containing sulfilimine (sulfonimine) compounds and their preparation method and use | UNIV NANKAI | 2012-12-12 | — | — | CN | disclosed |
| CN-102603670-A | 4-(4-methyl-1,2,3-thiadiazole-5-base)-3-alkene-2-ketone ramifications, and preparation method and application thereof | UNIV NANKAI | 2012-07-25 | — | — | CN | disclosed |
| CN-102532082-A | 2,2-dimethyl benzopyran compound and preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2012-07-04 | — | — | CN | disclosed |
| EP-2174934-B1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2012-06-06 | — | — | EP | disclosed |
| CN-102417505-A | Tetrazole compounds containing methyl-1,2,3-thiadiazole as well as preparation methods and application thereof | UNIV NANKAI | 2012-04-18 | — | — | CN | disclosed |
| EP-2394995-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | Kumiai Chemical Industry CO., LTD. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| CN-101260091-B | Acrylamides compounds containing 1,2,3-thiadiazoles ring and having anti-hepatitis B virus activity | UNIV NANKAI | 2011-07-06 | — | — | CN | disclosed |
| CN-101878219-A | Imidazothiadiazoles for use as protein kinase inhibitors | CT NAC DE INVESTIGACIONES ONCO | 2010-11-03 | — | — | CN | disclosed |
| CN-101817815-A | Compounds with antibacterial activity | MORPHOCHEM AG KOMB CHEMIE | 2010-09-01 | — | — | CN | disclosed |
| US-20100197674-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| EP-2174934-A1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-2167490-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2010-03-31 | — | — | EP | disclosed |
| CN-101687876-A | amino-heterocyclic compounds | PFIZER | 2010-03-31 | — | — | CN | disclosed |
| EP-1555257-B1 | PROCESS FOR PRODUCING AROMATIC NITRILE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2010-01-20 | — | — | EP | disclosed |
| CN-100569769-C | Compounds with fungicidal activity | MORPHOCHEM AG KOMB CHEMIE (DE) | 2009-12-16 | — | — | CN | disclosed |
| CN-101605783-A | Novel N, N' -2, 4-dianilinopyrimidine derivatives as drugs, pharmaceutical compositions, especially as IKK inhibitors, and preparation thereof | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | CN | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| WO-2008153325-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-12-18 | — | — | WO | disclosed |
| CN-101283995-A | Different pharmaceutical uses alpha2delta ligands | WARNER LAMBERT CO (US) | 2008-10-15 | — | — | CN | disclosed |
| CN-101260091-A | Acrylamides compounds containing 1,2,3-thiadiazoles ring and having anti-hepatitis B virus activity | UNIV NANKAI (CN) | 2008-09-10 | — | — | CN | disclosed |
| EP-1943222-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2008-07-16 | — | — | EP | disclosed |
| EP-1915907-A2 | An agricultural and horticultural disease controller | Nihon Nohyaku Co., Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |
| CN-101171255-A | Heterobicyclic acrylamides | BAYER CROPSCIENCE AG (DE) | 2008-04-30 | — | — | CN | disclosed |
| EP-1904479-A2 | NOVEL 2,4-DIANILINOPYRIMIDINE DERIVATIVES, THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND, IN PARTICULAR, AS IKK INHIBITORS | Sanofi-Aventis (FR) | 2008-04-02 | — | — | EP | disclosed |
| CN-101035784-A | New bicyclic antibiotics | ACTELION PHARMACEUTICALS LTD (CH) | 2007-09-12 | — | — | CN | disclosed |
| US-7262316-B2 | Process for producing aromatic nitrile compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1781650-A1 | NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2007042325-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2007-04-19 | — | — | WO | disclosed |
| CN-1926105-A | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof | ASTRAZENECA AB (SE) | 2007-03-07 | — | — | CN | disclosed |
| WO-2007006926-A2 | NOVEL 2,4-DIANILINOPYRIMIDINE DERIVATIVES, THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND, IN PARTICULAR, AS IKK INHIBITORS | SANOFI-AVENTIS (FR) | 2007-01-18 | — | — | WO | disclosed |
| CN-1878546-A | Combination comprising an alpha-2 delta ligand and an SSRI and/or SNRI for the treatment of depression and anxiety | WARNER LAMBERT CO (US) | 2006-12-13 | — | — | CN | disclosed |
| EP-1688041-A1 | An agricultural and horticultural disease controller and a method for controlling the diseases | Nihon Nohyaku Co., Ltd. (JP) | 2006-08-09 | — | — | EP | disclosed |
| US-20060094739-A1 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | ATP CAPITAL LP | 2006-05-04 | — | — | US | disclosed |
| US-20060069282-A1 | Process for producing aromatic nitrile compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
| WO-2006021448-A1 | NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2006-03-02 | — | — | WO | disclosed |
| CN-1726015-A | Alpha 2 delta ligands for different pharmaceutical uses | WARNER LAMBERT CO (US) | 2006-01-25 | — | — | CN | disclosed |
| WO-2005115148-A1 | 3-ARYL-3-HYDROXY-2-METHYLENEPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| CN-1703412-A | Novel compounds with fungicidal activity | MORPHOCHEM AG KOMB CHEMIE (DE) | 2005-11-30 | — | — | CN | disclosed |
| CN-1701069-A | 3,4-disubstituted pyrroles and their for use in treating inflammatory diseases | JANSSEN PHARMACEUTICA NV (BE) | 2005-11-23 | — | — | CN | disclosed |
| CN-1678298-A | Use of an alpha2delta ligand such as gabapentin or pregabalin for treating ttention deficit hyperactivity disorder | WARNER LAMBERT CO (US) | 2005-10-05 | — | — | CN | disclosed |
| CN-1214026-C | Indol-3-yl derivatives | MERCK PATENT GMBH (DE) | 2005-08-10 | — | — | CN | disclosed |
| EP-1555257-A1 | PROCESS FOR PRODUCING AROMATIC NITRILE COMPOUND | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |
| EP-1551829-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2005-07-13 | — | — | EP | disclosed |
| CN-1210268-C | ((Cyclo) alkyl substituted-.gamma.-aminobutyric acid derivatives (=GABA analogurs), their preparation and their use in the treatment of neurolog disorders | WARNER LAMBERT CO (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1635887-A | Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2 | WARNER LAMBERT CO (US) | 2005-07-06 | — | — | CN | disclosed |
| CN-1625393-A | Alpha 2 delta ligands to treat tinnitus | WARNER LAMBERT CO (US) | 2005-06-08 | — | — | CN | disclosed |
| EP-0824317-B1 | AN AGRICULTURAL AND HORTICULTURAL DISEASE CONTROLLER AND A METHOD FOR CONTROLLING THE DISEASES | NIHON NOHYAKU CO LTD (JP) | 2004-10-13 | — | — | EP | disclosed |
| CN-1535272-A | Nitrogen-containing bicyclic heterocycles | ʷ | 2004-10-06 | — | — | CN | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |
| EP-1413199-A1 | An agricultural and horticultural disease controller and a method for controlling the diseases | Nihon Nohyaku Co., Ltd. (JP) | 2004-04-28 | — | — | EP | disclosed |
| CN-1452619-A | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM PLC (GB) | 2003-10-29 | — | — | CN | disclosed |
| CN-1398264-A | Indol-3-yl derivatives | MERCK PATENT GMBH (DE) | 2003-02-19 | — | — | CN | disclosed |
| US-6521649-B1 | 1,2,3-thiadiazole derivatives; expanding spectrum of controllable diseases and period of time when effective applications are possible; reducing dosage | NIHON NOHAYKU CO., LTD. (JP) | 2003-02-18 | — | — | US | disclosed |
| CN-1072657-C | 1,2, 3-thiadiazole derivative and salt thereof, agrohorticultural virus control agent, and method for using same | NIHON NOHYAKU CO LTD (JP) | 2001-10-10 | — | — | CN | disclosed |
| US-6297374-B1 | Nitroimino-nitromethylene—azole or-azine heterocyclic compounds, insecticidal compositions containing them, and insecticidal methods of using them | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-02 | — | — | US | disclosed |
| CN-1279673-A | ((Cyclo) alkyl substituted-.gamma.-aminobutyric acid derivatives (=GABA analogurs), their preparation and their use in the treatment of neurolog disorders | WARNER LAMBERT CO (US) | 2001-01-10 | — | — | CN | disclosed |
| US-6166054-A | Agricultural and horticultural disease controller and a method for controlling the diseases | NIHON NOHYAKU CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| US-6022967-A | 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-08 | — | — | US | disclosed |
| CN-1232458-A | 1,2,3-thiadiazole derivs. and salts thereof, disease agent for agricultural and horticultural use and method for use thereof | NIHON NOHYAKU CO LTD (JP) | 1999-10-20 | — | — | CN | disclosed |
| US-5750704-A | INSECTICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0824317-A2 | AN AGRICULTURAL AND HORTICULTURAL DISEASE CONTROLLER AND A METHOD FOR CONTROLLING THE DISEASES | Nihon Nohyaku Co., Ltd. (JP) | 1998-02-25 | — | — | EP | disclosed |
| US-5580889-A | Insecticidal nitromethyl or niteoimino-heteromethyl-heterocyclics | NIHON BAYER AGROCHEM K.K. (JP) | 1996-12-03 | — | — | US | disclosed |
| WO-1996029871-A2 | AN AGRICULTURAL AND HORTICULTURAL DISEASE CONTROLLER AND A METHOD FOR CONTROLLING THE DISEASES | NIHON NOHYAKU CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |
| US-5461167-A | 2-chloro-5-chloromethyl thiazole; insecticide | NIHON BAYER AGROCHEM K.K. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5428032-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5298507-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5204360-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-5073551-A | Antibiotics | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-12-17 | — | — | US | disclosed |
| US-5001138-A | Insecticides | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| CN-1049013-A | The 4-heterocycle aroyl pyrazoles that replaces, preparation method and as the purposes of weedicide | SCHERING AG (DE) | 1991-02-06 | — | — | CN | disclosed |
| EP-0335390-A2 | Novel cephalosporin compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-10-04 | — | — | EP | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |