Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.39 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345637 | 0.86 | CYP4F2 (0.50) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4508144 | 0.78 | CYP4F2 (0.49) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15287206 | 0.78 | CYP4F2 (0.43) | CYP4F2CYP4A11LMNACA1CA2 | |
| SCHEMBL19900035 | 0.77 | CYP4Z1 (0.48) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2135765 | 0.77 | HTR2A (0.45) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14542484 | 0.77 | CYP4F2 (0.50) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9671446 | 0.76 | CYP4F2 (0.47) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9157019 | 0.76 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1511092 | 0.76 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7857892 | 0.75 | CYP4F2 (0.52) | CYP4F2CYP4A11CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7575785-B2 | use thereof in liquid-crystalline media, and and to electro-optical display elements containing these liquid-crystalline media; negative dielectric anisotropy | MERCK PATENT GMBH (DE) | 2009-08-18 | — | — | US | disclosed |
| US-7575785-B2 | use thereof in liquid-crystalline media, and and to electro-optical display elements containing these liquid-crystalline media; negative dielectric anisotropy | MERCK PATENT GMBH (DE) | 2009-08-18 | — | — | US | disclosed |