Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13756748 | 0.89 | CNR1 (0.65) | CNR1SMN1; SMN2RAB9ANPC1MAPT | |
| Cyclohexane SCHEMBL4696394 | 0.84 | CNR1 (0.55) | CNR1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL4697369 | 0.82 | CNR1 (0.55) | CNR1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL38658836 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL4469473 | 0.79 | CNR1 (1.00) | CNR1ALDH1A1 | |
| SCHEMBL4465606 | 0.77 | CNR1 (0.97) | CNR1ALDH1A1 | |
| SCHEMBL4695062 | 0.76 | CNR1 (0.65) | CNR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL416553 | 0.75 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL4697973 | 0.74 | CNR1 (0.56) | CNR1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL4051171 | 0.73 | RAB9A (0.69) | SMN1; SMN2RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576088-B2 | Benzodioxole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576088-B2 | Benzodioxole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2009-08-18 | — | — | US | disclosed |