Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FADS1 | O60427 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333075 | 0.94 | GSK3B (0.57) | GSK3BCDK1CDK2TRPA1GRM4 | |
| SCHEMBL2336326 | 0.92 | GSK3B (0.59) | GSK3BCDK1CDK2TRPA1FADS1 | |
| SCHEMBL1375716 | 0.85 | GSK3B (0.61) | GSK3BCDK1CDK2TRPA1FADS1 | |
| SCHEMBL6208060 | 0.84 | TRPA1 (0.55) | GSK3BCDK1CDK2TRPA1GRM4 | |
| SCHEMBL2334773 | 0.84 | GSK3B (0.62) | GSK3BCDK1CDK2TRPA1LMNA | |
| SCHEMBL1376062 | 0.83 | GSK3B (0.59) | GSK3BCDK1CDK2TRPA1GRM4 | |
| SCHEMBL2336289 | 0.82 | GSK3B (0.58) | GSK3BCDK1CDK2TRPA1GRM4 | |
| SCHEMBL2336016 | 0.79 | GSK3B (0.55) | GSK3BCDK1CDK2TRPA1ABCG2 | |
| SCHEMBL2332201 | 0.78 | GSK3B (0.57) | GSK3BCDK1CDK2ABCG2MAPT | |
| SCHEMBL1378090 | 0.78 | GSK3B (0.53) | GSK3BCDK1CDK2TRPA1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4764168-B2 | — | — | 2011-08-31 | — | — | JP | claimed |
| EP-1572200-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004062662-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-07-29 | — | — | WO | claimed |