Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88301 | 0.97 | — | — | |
| SCHEMBL13270524 | 0.94 | MAPT (0.35) | MAPTTDP1PIM1CYP3A4GRIN2D | |
| Methoxymethane SCHEMBL6106068 | 0.78 | GSR (0.32) | TDP1GAAKDM4E | |
| SCHEMBL239276 | 0.75 | CA9 (0.36) | MAPTTDP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8722443 | 0.73 | — | — | |
| SCHEMBL14071572 | 0.72 | CA9 (0.35) | MAPTTDP1CYP3A4KDM4EALDH1A1 | |
| Methyl Alcohol SCHEMBL28845780 | 0.71 | GSR (0.35) | MAPTTDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL7751523 | 0.71 | — | — | |
| SCHEMBL56172 | 0.71 | — | — | |
| SCHEMBL2871822 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879850-B1 | ACRYLIC ESTER COMPOUND AND MANUFACTURING INTERMEDIATE THEREOF, METHOD FOR MANUFACTURING ACRYLIC ESTER COMPOUND, AND LATENT ELECTROSTATIC IMAGE BEARING MEMBER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | RICOH CO LTD (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-8623577-B2 | Acrylic ester compound and manufacturing intermediate thereof, method for manufacturing acrylic ester compound, and latent electrostatic image bearing member, image forming method, image forming apparatus and process cartridge | RICOH COMPANY, LTD. (JP) | 2014-01-07 | — | — | US | disclosed |
| US-20110287353-A1 | ACRYLIC ESTER COMPOUND AND MANUFACTURING INTERMEDIATE THEREOF, METHOD FOR MANUFACTURING ACRYLIC ESTER COMPOUND, AND LATENT ELECTROSTATIC IMAGE BEARING MEMBER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-1879850-A1 | ACRYLIC ESTER COMPOUND AND MANUFACTURING INTERMEDIATE THEREOF, METHOD FOR MANUFACTURING ACRYLIC ESTER COMPOUND, AND LATENT ELECTROSTATIC IMAGE BEARING MEMBER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | Ricoh Company, Ltd. (JP) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006121187-A1 | ACRYLIC ESTER COMPOUND AND MANUFACTURING INTERMEDIATE THEREOF, METHOD FOR MANUFACTURING ACRYLIC ESTER COMPOUND, AND LATENT ELECTROSTATIC IMAGE BEARING MEMBER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287353-A1 | ACRYLIC ESTER COMPOUND AND MANUFACTURING INTERMEDIATE THEREOF, METHOD FOR MANUFACTURING ACRYLIC ESTER COMPOUND, AND LATENT ELECTROSTATIC IMAGE BEARING MEMBER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | C9, PAM, NAA15 | MAPT 2965/4885TDP1 4706/4885PIM1 1949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.