Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.34 |
| ▸ | RELA | Q04206 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10196867 | 0.79 | FES (0.41) | GAAKMT2ARAB9ANPC1KDM4E | |
| SCHEMBL1602848 | 0.79 | FES (0.41) | GAAKMT2ARAB9ANPC1KDM4E | |
| SCHEMBL13759268 | 0.74 | PIKFYVE (0.46) | GAAKMT2ARAB9ANPC1KDM4E | |
| SCHEMBL14530768 | 0.72 | ESR1 (0.37) | L3MBTL1 | |
| SCHEMBL14530003 | 0.70 | FES (0.45) | GAAKMT2ARAB9ANPC1KDM4E | |
| SCHEMBL430704 | 0.69 | SYK (0.44) | GAAKMT2ARAB9ANPC1KDM4E | |
| SCHEMBL10198817 | 0.69 | SYK (0.44) | GAAKMT2ARAB9ANPC1KDM4E | |
| SCHEMBL430705 | 0.69 | SYK (0.44) | GAAKMT2ARAB9ANPC1KDM4E | |
| SCHEMBL14530781 | 0.69 | FES (0.40) | GAAKMT2ARAB9ANPC1KDM4E | |
| SCHEMBL427676 | 0.69 | FES (0.42) | GAAKMT2ARAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100406-A2 | TOPICAL FORMULATIONS FOR THE TREATMENT OF PSORIASIS | SYNTA PHARMACEUTICALS CORP. (US) | 2009-08-13 | — | — | WO | disclosed |