Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | TST | Q16762 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494394 | 0.94 | VDR (0.46) | VDR | |
| SCHEMBL14489015 | 0.89 | VDR (0.46) | VDRLMNAARALDH1A1ALOX15 | |
| SCHEMBL12749793 | 0.86 | VDR (0.49) | VDR | |
| SCHEMBL14494383 | 0.86 | VDR (0.49) | VDR | |
| SCHEMBL19670744 | 0.86 | VDR (0.49) | VDR | |
| SCHEMBL3184891 | 0.86 | VDR (0.53) | VDR | |
| SCHEMBL14523030 | 0.86 | VDR (0.52) | VDR | |
| SCHEMBL10019067 | 0.84 | VDR (0.52) | VDR | |
| SCHEMBL13297559 | 0.84 | VDR (0.52) | VDR | |
| SCHEMBL13525348 | 0.84 | VDR (0.52) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563783-B2 | 2-methylene-19-nor-(20S-24S)-1α,25-dihydroxyvitamin-D2 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-07-21 | — | — | US | disclosed |
| US-7511030-B2 | 2-methylene-19-nor-(20S-24epi)-1α,25-dihydroxyvitamin D2 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-03-31 | — | — | US | disclosed |