Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643088 | 0.91 | PTGDR2 (0.44) | PTGDR2TBXA2RPTGDRFFAR1FFAR2 | |
| SCHEMBL13760999 | 0.90 | PTGDR2 (0.46) | PTGDR2TBXA2RPTGDRFFAR1FFAR2 | |
| SCHEMBL1644127 | 0.90 | DRD2 (0.45) | PTGDR2TBXA2RPTGDRFFAR1FFAR2 | |
| SCHEMBL1945418 | 0.87 | PTGDR2 (0.47) | PTGDR2TBXA2RPTGDRFFAR1FFAR2 | |
| SCHEMBL2278477 | 0.86 | CYP3A4 (0.54) | PTGDR2TBXA2RPTGDRFFAR1FFAR2 | |
| SCHEMBL2275749 | 0.85 | PTGDR2 (0.41) | PTGDR2TBXA2RPTGDRFFAR1FFAR2 | |
| SCHEMBL1009816 | 0.85 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1944008 | 0.84 | PTGDR2 (0.64) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL2279317 | 0.84 | PPARG (0.51) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1058954 | 0.84 | PTGDR2 (0.52) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102893-A2 | CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 receptors | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |