Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13754272 | 0.92 | ALDH1A1 (0.74) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL13761468 | 0.92 | ALDH1A1 (0.74) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL13753583 | 0.85 | ALDH1A1 (0.65) | ALDH1A1LMNASMN1; SMN2KMT2ANR1H4 | |
| SCHEMBL13754282 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL13754268 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL13753788 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL13761628 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL13753371 | 0.85 | ALDH1A1 (0.71) | ALDH1A1LMNASMN1; SMN2KMT2ANR1H4 | |
| SCHEMBL13753830 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2KMT2ANR1H4 | |
| SCHEMBL13754119 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2KMT2ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |