Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 4/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335033 | 0.96 | GSK3B (0.52) | GSK3BCDK1CDK2GRM4TRPA1 | |
| SCHEMBL2336016 | 0.93 | GSK3B (0.55) | GSK3BCDK1CDK2TRPA1ABCG2 | |
| SCHEMBL6528861 | 0.87 | CDK1 (0.49) | GSK3BCDK1CDK2GRM4TRPA1 | |
| SCHEMBL1378090 | 0.85 | GSK3B (0.53) | GSK3BCDK1CDK2GRM4TRPA1 | |
| SCHEMBL1376062 | 0.85 | GSK3B (0.59) | GSK3BCDK1CDK2GRM4TRPA1 | |
| SCHEMBL6206393 | 0.84 | TRPA1 (0.51) | GSK3BCDK1CDK2GRM4TRPA1 | |
| SCHEMBL2334773 | 0.84 | GSK3B (0.62) | GSK3BCDK1CDK2TRPA1FADS1 | |
| SCHEMBL2338742 | 0.80 | GSK3B (0.57) | GSK3BCDK1CDK2EPHX2 | |
| SCHEMBL4380398 | 0.80 | GSK3B (0.62) | GSK3BCDK1CDK2KDRFLT1 | |
| SCHEMBL4485622 | 0.79 | GRM4 (0.53) | GSK3BCDK1CDK2GRM4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4764168-B2 | — | — | 2011-08-31 | — | — | JP | claimed |