Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.70 |
| ▸ | CNR2 | P34972 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075297 | 0.90 | ACKR3 (0.70) | ACKR3CNR2TP53LMNAMAPT | |
| SCHEMBL1071036 | 0.89 | ACKR3 (0.69) | ACKR3CNR2TP53LMNAMAPT | |
| SCHEMBL13762969 | 0.89 | ACKR3 (0.75) | ACKR3CNR2TP53LMNAMAPT | |
| SCHEMBL1073155 | 0.89 | ACKR3 (0.70) | ACKR3CNR2TP53LMNAMAPT | |
| SCHEMBL12707290 | 0.88 | ACKR3 (0.55) | ACKR3CNR2TP53LMNAMAPT | |
| SCHEMBL12707393 | 0.88 | ACKR3 (0.59) | ACKR3CNR2TP53LMNAMAPT | |
| SCHEMBL1075081 | 0.88 | ACKR3 (0.69) | ACKR3CNR2TP53LMNAMAPT | |
| SCHEMBL1075380 | 0.88 | ACKR3 (0.69) | ACKR3CNR2TP53LMNAMAPT | |
| SCHEMBL1073977 | 0.87 | ACKR3 (0.66) | ACKR3CNR2TP53LMNAMAPT | |
| SCHEMBL1083065 | 0.86 | ACKR3 (0.67) | ACKR3CNR2TP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557213-B2 | Substituted quinolones and methods of use | CHEMOCENTRYX, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-7557213-B2 | Substituted quinolones and methods of use | CHEMOCENTRYX, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20070167443-A1 | Substituted quinolones and methods of use | CHEMOCENTRYX, INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070167443-A1 | Substituted quinolones and methods of use | CHEMOCENTRYX, INC. (US) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167443-A1 | Substituted quinolones and methods of use | TOP2A, NQO2, TOP2B | ACKR3 3624/4885CNR2 2729/4885TP53 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.