Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2759554 | 0.79 | L3MBTL1 (0.38) | GAAALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL85558 | 0.76 | CA1 (0.44) | ALDH1A1L3MBTL1HTT | |
| SCHEMBL13768117 | 0.76 | USP2 (0.33) | GAAL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL85557 | 0.74 | NPSR1 (0.35) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13799203 | 0.71 | GAA (0.33) | GAAALDH1A1L3MBTL1 | |
| SCHEMBL3220299 | 0.70 | KMT2A (0.45) | GAAALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL85044 | 0.69 | CA1 (0.35) | ALDH1A1LMNAHTT | |
| SCHEMBL92825 | 0.69 | CHRNB4 (0.35) | GAAALDH1A1 | |
| SCHEMBL12880363 | 0.68 | SCN9A (0.37) | GAAALDH1A1L3MBTL1 | |
| SCHEMBL85214 | 0.67 | CA1 (0.43) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563785-B2 | Quetiapine analogs and methods of use thereof | HYPNION, INC. (US) | 2009-07-21 | — | — | US | disclosed |
| US-7482460-B2 | Doxepin analogs and methods of use thereof | HYPNION, INC. (US) | 2009-01-27 | — | — | US | disclosed |