SCHEMBL1376447

SCHEMBL1376447

CN(C)c1ccccc1-c1ccc(C(c2ccc(-c3ccccc3N(C)C)cc2)C(OC(c2ccccc2)C(c2ccc(-c3ccccc3N(C)C)cc2)c2ccc(-c3ccccc3N(C)C)cc2)c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
NSD2 O96028 1/20 0.35
EGFR P00533 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CNR2 P34972 1/20 0.34
GRM5 P41594 1/20 0.33
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GRIA4 P48058 1/20 0.31
METAP2 P50579 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4909538 0.80 ALDH1A1 (0.46) ALDH1A1NSD2EGFRLMNAMAPT
SCHEMBL367772 0.77 ALDH1A1 (0.46) ALDH1A1MAPK1TDP1L3MBTL1CNR2
SCHEMBL19698852 0.76 MAPT (0.47) ALDH1A1NSD2EGFRLMNAMAPT
SCHEMBL29433183 0.74 ALDH1A1 (0.45) ALDH1A1NSD2EGFRLMNAMAPT
SCHEMBL1254512 0.74 ALDH1A1 (0.45) ALDH1A1NSD2EGFRLMNAMAPT
SCHEMBL8650691 0.72 CNR2 (0.40) ALDH1A1NSD2EGFRLMNAMAPT
SCHEMBL27517786 0.72 ALDH1A1 (0.44) ALDH1A1NSD2EGFRLMNAMAPT
SCHEMBL30763243 0.72 ALDH1A1 (0.44) ALDH1A1NSD2EGFRLMNAMAPT
SCHEMBL27516508 0.72 ALDH1A1 (0.44) ALDH1A1NSD2EGFRLMNAMAPT
Hydrochloric Acid SCHEMBL2866856 0.72 ALDH1A1 (0.44) ALDH1A1NSD2EGFRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2554392-B1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR MANUFACTURING THE SAME MITSUBISHI PAPER MILLS LTD (JP) 2016-05-11 EP disclosed
US-8980791-B2 Thermal recording material and method for producing the same MITSUBISHI PAPER MILLS LIMITED (JP) 2015-03-17 US disclosed
EP-2096149-B1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED MITSUBISHI PAPER MILLS LTD (JP) 2014-10-22 EP disclosed
US-8623785-B2 Thermal recording material and method for producing the same MITSUBISHI PAPER MILLS LIMITED (JP) 2014-01-07 US disclosed
US-20140005046-A1 THERMAL RECORDING MATERIAL AND METHOD FOR PRODUCING THE SAME MITSUBISHI PAPER MILLS LIMITED (JP) 2014-01-02 US disclosed
US-8598075-B2 Thermal recording material and method for producing the same MITSUBISHI PAPER MILLS LIMITED (JP) 2013-12-03 US disclosed
US-8410019-B2 Modifying agent for coating composition for producing protective layer in thermosensitive recording medium, coating composition for protective layer in thermosensitive recording medium, and thermosensitive recording medium using the same DIC CORPORATION (JP) 2013-04-02 US disclosed
US-20130053240-A1 THERMAL RECORDING MATERIAL AND METHOD FOR PRODUCING THE SAME MITSUBISHI PAPER MILLS LIMITED (JP) 2013-02-28 US disclosed
EP-2554392-A1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR MANUFACTURING THE SAME Mitsubishi Paper Mills Limited (JP) 2013-02-06 EP disclosed
US-20120329646-A1 THERMAL RECORDING MATERIAL AND METHOD FOR PRODUCING THE SAME MITSUBISHI PAPER MILLS LIMITED (JP) 2012-12-27 US disclosed
US-20030070339-A1 Rewritable thermal label of a non-contact type and method for using the label LINTEC CORPORATION (JP) 2003-04-17 US disclosed
US-6184180-B1 COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE MITSUBISHI PAPER MILLS LIMITED (JP) 2001-02-06 US disclosed
EP-0754564-B1 Heat sensitive recording material and recording method. MITSUBISHI PAPER MILLS LTD (JP) 2000-03-01 EP disclosed
US-6004899-A SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1999-12-21 US disclosed
US-5876898-A MULTICOLOR RECORDING OF HIGH CONTRAST MITSUBISHI PAPER MILLS LIMITED (JP) 1999-03-02 US disclosed
US-5817599-A COLORLESS DYE PRECURSOR AND REVERSIBLE COLOR DEVELOPER MITSUBISHI PAPER MILLS LIMITED (JP) 1998-10-06 US disclosed
EP-0574879-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1997-05-02 EP disclosed
EP-0754564-A2 Heat sensitive recording material and recording method using the same MITSUBISHI PAPER MILLS, LTD. (JP) 1997-01-22 EP disclosed
US-5395815-A Phenolic compound electron acceptor; images; contrast; stability MITSUBISHI PAPER MILLS LIMITED (JP) 1995-03-07 US disclosed
EP-0574879-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1993-12-22 EP disclosed