Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 14/20 | 0.70 |
| ▸ | SLC5A1 | P13866 | 11/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | IL2 | P60568 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729084 | 0.92 | SLC5A2 (0.59) | SLC5A2SLC5A1ACHE | |
| SCHEMBL13764485 | 0.90 | SLC5A2 (0.58) | SLC5A2SLC5A1NPC1RAB9A | |
| SCHEMBL13764481 | 0.90 | SLC5A2 (0.56) | SLC5A2SLC5A1 | |
| SCHEMBL1728328 | 0.87 | SLC5A2 (0.69) | SLC5A2SLC5A1NPC1RAB9AIL2 | |
| SCHEMBL1728347 | 0.86 | SLC5A1 (0.54) | SLC5A2SLC5A1NPC1RAB9AIL2 | |
| SCHEMBL13110378 | 0.83 | SLC5A2 (1.00) | SLC5A2SLC5A1 | |
| SCHEMBL1728250 | 0.81 | SLC5A2 (0.60) | SLC5A2SLC5A1 | |
| SCHEMBL13764480 | 0.80 | SLC5A2 (0.57) | SLC5A2SLC5A1NPC1RAB9AIL2 | |
| SCHEMBL1727955 | 0.79 | SLC28A3 (0.52) | SLC5A2SLC5A1NPC1RAB9A | |
| SCHEMBL2700557 | 0.79 | SLC5A2 (0.53) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566699-B2 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| US-7566699-B2 | Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-28 | — | — | US | disclosed |