SCHEMBL13764481

SCHEMBL13764481

Cc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2c(CCc3ccccc3)coc2c1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 16/20 0.56
▸ SLC5A1 P13866 12/20 0.56
▸ EPHX2 P34913 1/20 0.47
▸ POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1729084 0.93 SLC5A2 (0.59) SLC5A2SLC5A1EPHX2POLB
SCHEMBL13764484 0.90 SLC5A2 (0.70) SLC5A2SLC5A1
SCHEMBL1727955 0.89 SLC28A3 (0.52) SLC5A2SLC5A1EPHX2
SCHEMBL1728347 0.89 SLC5A1 (0.54) SLC5A2SLC5A1EPHX2
SCHEMBL13764485 0.87 SLC5A2 (0.58) SLC5A2SLC5A1POLB
SCHEMBL1728291 0.86 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL1726690 0.86 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL1728404 0.83 SLC5A2 (0.53) SLC5A2SLC5A1EPHX2
SCHEMBL1728250 0.83 SLC5A2 (0.60) SLC5A2SLC5A1
SCHEMBL1728107 0.81 SLC5A2 (0.53) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140212473-A1 GLYCOPEPTIDE AND USES THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2014-07-31 — — US disclosed
US-7566699-B2 Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-07-28 — — US disclosed
US-7566699-B2 Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140212473-A1 GLYCOPEPTIDE AND USES THEREOF LGALS3BP, SIGLEC7, LNPEP SLC5A2 834/4885SLC5A1 984/4885EPHX2 2124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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