Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 12/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1376484 | 1.00 | MAPK8 (0.38) | MAPK8MAPK9KDM4EMEN1NPC1 | |
| SCHEMBL1378900 | 0.92 | MAPK8 (0.41) | MAPK8MAPK9SYK | |
| SCHEMBL1378906 | 0.92 | MAPK8 (0.41) | MAPK8MAPK9SYK | |
| SCHEMBL5205593 | 0.92 | MAPK8 (0.41) | MAPK8MAPK9SYK | |
| SCHEMBL5205582 | 0.92 | MAPK8 (0.41) | MAPK8MAPK9SYK | |
| SCHEMBL1378901 | 0.92 | MAPK8 (0.41) | MAPK8MAPK9SYK | |
| SCHEMBL1376073 | 0.91 | KDM4E (0.39) | MAPK8KDM4EMEN1NPC1MAPT | |
| SCHEMBL1376071 | 0.91 | KDM4E (0.39) | MAPK8KDM4EMEN1NPC1MAPT | |
| SCHEMBL5202820 | 0.91 | KDM4E (0.41) | MAPK8KDM4EMEN1NPC1MAPT | |
| SCHEMBL5206452 | 0.91 | KDM4E (0.41) | MAPK8KDM4EMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4743463-B2 | — | — | 2011-08-10 | — | — | JP | claimed |