Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 7/20 | 0.59 |
| ▸ | HRH1 | P35367 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044318 | 1.00 | HRH2 (0.59) | HRH2HRH1KDM4EDRD2MAPT | |
| SCHEMBL13044339 | 0.88 | HRH2 (0.58) | HRH2HRH1KDM4EDRD2MAPT | |
| SCHEMBL13078381 | 0.86 | HRH2 (0.57) | HRH2HRH1KDM4EDRD2MAPT | |
| Hydrochloric Acid SCHEMBL23247221 | 0.86 | KDM4E (0.69) | HRH2HRH1KDM4EDRD2MAPT | |
| SCHEMBL31707039 | 0.84 | KDM4E (0.61) | HRH2HRH1KDM4EMAPTMEN1 | |
| SCHEMBL13765525 | 0.82 | KDM4E (0.55) | HRH2HRH1KDM4EDRD2MAPT | |
| SCHEMBL2089311 | 0.81 | KDM4E (0.78) | HRH2HRH1KDM4EDRD2MAPT | |
| SCHEMBL9200735 | 0.81 | HRH3 (0.72) | HRH2HRH1MAPTMEN1ALDH1A1 | |
| SCHEMBL27568839 | 0.81 | HRH3 (0.55) | HRH2HRH1KDM4EDRD2MAPT | |
| SCHEMBL7250762 | 0.80 | KDM4E (0.70) | HRH2HRH1KDM4EDRD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980221-B2 | Fluoride processing method | GE HEALTHCARE LIMITED (GB) | 2015-03-17 | — | — | US | disclosed |
| WO-2009083530-A2 | FLUORIDE PROCESSING METHOD | GE HEALTHCARE LIMITED (GB) | 2009-07-09 | — | — | WO | disclosed |