Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753002 | 0.92 | MAPT (0.55) | TP53NPC1RAB9APKMKMT2A | |
| SCHEMBL10179953 | 0.89 | RAB9A (0.47) | TP53NPC1RAB9APKMKMT2A | |
| SCHEMBL10180279 | 0.87 | RAB9A (0.46) | TP53NPC1RAB9APKMKMT2A | |
| SCHEMBL3752697 | 0.86 | TP53 (0.70) | TP53NPC1RAB9APKMKMT2A | |
| SCHEMBL10181833 | 0.85 | MAPT (0.54) | TP53NPC1RAB9APKMKMT2A | |
| SCHEMBL3761084 | 0.84 | NPC1 (0.54) | TP53NPC1RAB9APKMKMT2A | |
| SCHEMBL3760855 | 0.83 | NPC1 (0.52) | TP53NPC1RAB9APKMKMT2A | |
| SCHEMBL3752826 | 0.82 | MAPT (0.52) | TP53NPC1RAB9AMAPTPOLB | |
| SCHEMBL3755950 | 0.82 | MAPT (0.49) | TP53NPC1RAB9APKMKMT2A | |
| SCHEMBL10181626 | 0.81 | NPC1 (0.48) | TP53NPC1RAB9APKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080663-A1 | TRIAZOLE OXADIAZOLES DERIVATIVES | MERCK SERONO S.A. (CH) | 2009-07-02 | — | — | WO | disclosed |