Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853423 | 0.84 | BCHE (0.40) | LTA4HEGFRLCKJAK3BTK | |
| SCHEMBL14850283 | 0.81 | CACNA1H (0.49) | EGFRLCKJAK3BTKKDM4E | |
| SCHEMBL13743 | 0.80 | BCHE (0.43) | LTA4HBCHE | |
| SCHEMBL14394 | 0.80 | LTA4H (0.43) | LTA4HBCHE | |
| SCHEMBL13781 | 0.80 | LTA4H (0.43) | LTA4HBCHE | |
| SCHEMBL14250 | 0.80 | LTA4H (0.43) | LTA4HBCHE | |
| SCHEMBL31293958 | 0.74 | LTA4H (0.55) | LTA4H | |
| SCHEMBL16993049 | 0.72 | KMT2A (0.43) | KDM4E | |
| SCHEMBL22654835 | 0.72 | KMT2A (0.43) | KDM4E | |
| SCHEMBL17277607 | 0.72 | KDM4E (0.55) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |