Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284960 | 0.89 | BCL2L1 (0.58) | BCL2L1BADCES1ACACBACACA | |
| SCHEMBL20112700 | 0.89 | CES1 (0.52) | BCL2L1BADCES1MEN1KMT2A | |
| SCHEMBL16239399 | 0.85 | BCL2L1 (0.52) | BCL2L1BADCES1MAOAMAOB | |
| SCHEMBL15203248 | 0.80 | BCL2L1 (0.48) | BCL2L1BADCES1ACACBACACA | |
| SCHEMBL16646844 | 0.79 | BCL2L1 (0.52) | BCL2L1BADCES1MAOAMEN1 | |
| SCHEMBL31187234 | 0.78 | ALDH1A1 (0.46) | BCL2L1BADCES1ACACBACACA | |
| SCHEMBL16527208 | 0.78 | BCL2L1 (0.50) | BCL2L1BADCES1MAOAMEN1 | |
| SCHEMBL31280589 | 0.77 | BCL2L1 (0.50) | BCL2L1BADCES1ACACBACACA | |
| SCHEMBL20040537 | 0.77 | MEN1 (0.46) | BCL2L1BADCES1ACACBACACA | |
| SCHEMBL1660189 | 0.77 | BCL2L1 (0.48) | BCL2L1BADCES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025839-A1 | METHOD OF SYNTHESIS | UNIVERSITY OF DURHAM (GB) | 2024-01-25 | — | — | US | disclosed |
| EP-1885732-B1 | CHIRAL DIPHOSPHONITES AS LIGANDS IN THE RUTHENIUM-CATALYSED ENANTIOSELECTIVE REDUCTION OF KETONES ß-KETO-ESTERS AND KETIMINES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-07-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025839-A1 | METHOD OF SYNTHESIS | NIT2, NAA15, ASNS | BCL2L1 4857/4885BAD 3999/4885CES1 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.