Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.70 |
| ▸ | CTSK | P43235 | 8/20 | 0.59 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13767153 | 0.90 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL13767146 | 0.86 | CAPN1 (0.80) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL13767147 | 0.86 | CAPN1 (0.80) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL5191078 | 0.84 | CTSK (0.64) | CAPN1CTSKCTSLCTSSCTSB | |
| SCHEMBL3356316 | 0.82 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL31705215 | 0.81 | CAPN1 (0.74) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL27809377 | 0.81 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL9828791 | 0.81 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL7327426 | 0.81 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSSHTRA1 | |
| SCHEMBL12829138 | 0.81 | CTSK (0.64) | CAPN1CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115390-B1 | HYDROXAMATE-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON INC (US) | 2009-07-22 | — | — | EP | disclosed |