Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205813 | 0.84 | GAA (0.40) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3363708 | 0.82 | IDO1 (0.38) | MTNR1AMTNR1BLMNAALDH1A1MAPT | |
| SCHEMBL21316223 | 0.72 | HSD17B3 (0.38) | NOTUMHSD17B3MTNR1AMTNR1BMEN1 | |
| SCHEMBL1143179 | 0.71 | PARP1 (0.36) | MEN1KMT2ARECQLCYP2D6 | |
| SCHEMBL15233622 | 0.71 | PARP1 (0.36) | MEN1KMT2ARECQLCYP2D6 | |
| SCHEMBL8161816 | 0.71 | CYP19A1 (0.37) | KDM4E | |
| SCHEMBL2524855 | 0.71 | PARP1 (0.36) | SMN1; SMN2MAPTKDM4EGAA | |
| SCHEMBL30317868 | 0.71 | CYP19A1 (0.37) | KDM4E | |
| SCHEMBL947069 | 0.70 | NAMPT (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19152096 | 0.68 | ALDH1A1 (0.41) | NOTUMHSD17B3MTNR1AMTNR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414783-B1 | METHOD FOR THE PRODUCTION OF AMINES BY REDUCTIVE AMINATION OF CARBONYL COMPOUNDS UNDER TRANSFER-HYDROGENATION CONDITIONS | EVONIK DEGUSSA GMBH (DE) | 2009-07-15 | — | — | EP | disclosed |