Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 12/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781079 | 0.84 | PTGES2 (0.81) | PTGES2USP2 | |
| SCHEMBL3780960 | 0.77 | PTGES2 (0.81) | PTGES2 | |
| SCHEMBL3782599 | 0.75 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL13639463 | 0.74 | PTGES2 (0.71) | PTGES2PYGL | |
| SCHEMBL3784257 | 0.73 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL13639465 | 0.72 | PTGES2 (0.67) | PTGES2PYGL | |
| SCHEMBL3782425 | 0.71 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3777997 | 0.71 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3782831 | 0.71 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3778531 | 0.69 | PTGES2 (1.00) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082347-A1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |