Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12193850 | 0.84 | GAA (0.41) | SMN1; SMN2TP53GAAHPGDALDH1A1 | |
| SCHEMBL12436920 | 0.69 | GAA (0.46) | SMN1; SMN2TP53GAAHPGDPOLB | |
| SCHEMBL11842319 | 0.69 | SMN1; SMN2 (0.35) | SMN1; SMN2TP53GAAHPGDALDH1A1 | |
| SCHEMBL890089 | 0.69 | CYP1A2 (0.44) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL12436922 | 0.68 | HPGD (0.58) | SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL2647862 | 0.67 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53GAAHPGDALDH1A1 | |
| SCHEMBL190928 | 0.67 | CYP1A2 (0.48) | SMN1; SMN2 | |
| SCHEMBL16360134 | 0.67 | SMN1; SMN2 (0.34) | SMN1; SMN2TP53GAAHPGDALDH1A1 | |
| SCHEMBL14108542 | 0.67 | SMN1; SMN2 (0.34) | SMN1; SMN2TP53GAAHPGDALDH1A1 | |
| SCHEMBL12807422 | 0.67 | SMN1; SMN2 (0.34) | SMN1; SMN2TP53GAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080795-A1 | EFFICIENT ASPIRIN PRODRUGS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2009-07-02 | — | — | WO | disclosed |