Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27585862 | 0.86 | — | — | |
| SCHEMBL27598302 | 0.86 | — | — | |
| SCHEMBL11842319 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2GAATP53ALDH1A1LMNA | |
| SCHEMBL890089 | 0.77 | CYP1A2 (0.44) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5074242 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL994667 | 0.77 | LMNA (0.44) | SMN1; SMN2LMNATSHRHPGD | |
| SCHEMBL12587490 | 0.76 | GAA (0.44) | SMN1; SMN2GAAALDH1A1LMNATSHR | |
| SCHEMBL190928 | 0.75 | CYP1A2 (0.48) | SMN1; SMN2 | |
| SCHEMBL16360134 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2GAATP53ALDH1A1LMNA | |
| SCHEMBL14108542 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2GAATP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096744-A1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| US-7582769-B2 | Dicycloalkyl urea glucokinase activators | NOVO NORDISK A/S (DK) | 2009-09-01 | — | — | US | disclosed |
| EP-1904466-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006760-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |
| US-4166117-A | HYPOTENSIVES | SCIENCE UNION ET CIE (FR) | 1979-08-28 | — | — | US | disclosed |