Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.60 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KHK | P50053 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PYGM | P11217 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30129078 | 0.79 | KDM4E (0.54) | KDM4EPLAURRAB9ANPC1ALDH1A1 | |
| SCHEMBL28663931 | 0.79 | KDM4E (0.54) | KDM4EPLAURRAB9ANPC1ALDH1A1 | |
| SCHEMBL30868882 | 0.78 | PLAUR (0.51) | KDM4EPLAURRAB9ANPC1ALDH1A1 | |
| SCHEMBL1589916 | 0.76 | PLAUR (0.61) | KDM4EPLAURRAB9ANPC1ALDH1A1 | |
| SCHEMBL30617972 | 0.76 | PLAUR (0.61) | KDM4EPLAURRAB9ANPC1ALDH1A1 | |
| SCHEMBL29992538 | 0.75 | KDM4E (1.00) | KDM4EPLAURRAB9ANPC1ALDH1A1 | |
| SCHEMBL1905589 | 0.75 | KDM4E (1.00) | KDM4EPLAURRAB9ANPC1ALDH1A1 | |
| SCHEMBL29367169 | 0.73 | POLB (0.65) | KDM4ERAB9ANPC1ALDH1A1NPSR1 | |
| SCHEMBL374735 | 0.73 | POLB (0.65) | KDM4ERAB9ANPC1ALDH1A1NPSR1 | |
| SCHEMBL111843 | 0.72 | POLB (0.62) | KDM4ERAB9ANPC1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085879-A2 | C20-C21 SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | SCHERING CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |