SCHEMBL111843

SCHEMBL111843

CSc1nc2ccccc2[nH]1.[Zn]

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.62
BCHE P06276 1/20 0.61
TXN P10599 2/20 0.61
SMN1; SMN2 Q16637 6/20 0.57
RAB9A P51151 5/20 0.57
NPC1 O15118 4/20 0.57
ALDH1A1 P00352 3/20 0.57
KDM4E B2RXH2 2/20 0.57
ABCB11 O95342 1/20 0.57
TP53 P04637 1/20 0.57
PKM P14618 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
HSD17B10 Q99714 1/20 0.57
HPGD P15428 2/20 0.56
EPHX2 P34913 1/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
AR P10275 1/20 0.53
MAPT P10636 1/20 0.51
STAT3 P40763 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29458312 1.00 POLB (0.62) POLBBCHETXNSMN1; SMN2RAB9A
SCHEMBL374735 0.98 POLB (0.65) POLBBCHETXNSMN1; SMN2RAB9A
SCHEMBL29367169 0.98 POLB (0.65) POLBBCHETXNSMN1; SMN2RAB9A
Hydrochloric Acid SCHEMBL9066571 0.96 POLB (0.62) POLBBCHETXNSMN1; SMN2RAB9A
Pyridine SCHEMBL27449114 0.88 POLB (0.54) POLBBCHETXNSMN1; SMN2RAB9A
SCHEMBL31019381 0.83 TXN (0.70) POLBBCHETXNSMN1; SMN2RAB9A
SCHEMBL3688773 0.83 TXN (0.70) POLBBCHETXNSMN1; SMN2RAB9A
SCHEMBL3792726 0.81 BCHE (0.68) POLBBCHETXNSMN1; SMN2RAB9A
SCHEMBL159798 0.81 TXN (0.72) POLBBCHETXNSMN1; SMN2RAB9A
SCHEMBL22292431 0.78 BCHE (0.69) POLBBCHETXNSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929983-A Wear-resistant novel rubber for mountaineering boots 扬州凯丰鞋业有限公司 2022-01-14 CN claimed
US-20200392316-A1 VULCANIZED HNBR PRODUCT WITH IMPROVED HOT AIR ARLANXEO DEUTSCHLAND GMBH (DE) 2020-12-17 US claimed
EP-3728452-A1 VULCANIZED HNBR PRODUCT WITH IMPROVED HOT AIR RESISTANCE ARLANXEO Deutschland GmbH (DE) 2020-10-28 EP claimed
CN-111492002-A Cured HNBR products having improved hot air resistance 阿朗新科德国有限责任公司 2020-08-04 CN claimed
CN-101624456-B Screw pump rubber stator material and preparation method thereof HARBIN INST OF TECHNOLOGY 2011-07-06 CN claimed
CN-101649078-B Hydrogenated nitrile-butadiene rubber modified by rectorite and preparation method thereof HARBIN INST OF TECHNOLOGY 2011-05-04 CN claimed
CN-101649078-A Hydrogenated nitrile-butadiene rubber modified by rectorite and preparation method thereof HARBIN INST OF TECHNOLOGY 2010-02-17 CN claimed
CN-101624456-A Screw pump rubber stator material and preparation method thereof HARBIN INST OF TECHNOLOGY 2010-01-13 CN claimed
CN-101338819-A L-shaped slip-ring sealed ring GUANGZHOU MECHANICAL ENGINEERI (CN) 2009-01-07 CN claimed
EP-4739514-A1 RUBBER MIXTURES CONTAINING POLYETHYLENEIMINE AND AT LEAST ONE PROCESSING AID CONTAINING AT LEAST ONE FATTY ACID LANXESS Deutschland GmbH (DE) 2026-05-13 EP disclosed
EP-3902855-B1 PULVERULENT MIXTURE OF PRECROSSLINKED NITRILE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2026-05-06 EP disclosed
EP-4724523-A1 ANTIVIBRATION RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2026-04-15 EP disclosed
US-20250368808-A1 RUBBER BLENDS CONTAINING AT LEAST ONE FUNCTIONALIZED SYNTHETIC RUBBER AND AT LEAST ONE ETHOXYLATED ALCOHOL LANXESS DEUTSCHLAND GMBH (DE) 2025-12-04 US disclosed
WO-2025108885-A1 RUBBER MIXTURES CONTAINING AT LEAST ONE PROCESSING AID OF FORMULA (I) LANXESS DEUTSCHLAND GMBH (DE) 2025-05-30 WO disclosed
US-20060106171-A1 Peroxide curable rubber composition comprising HNBR LANXESS INC. (CA) 2006-05-18 US disclosed
EP-1539828-A1 A PROCESS FOR THE PREPARATION OF A HYDROGENATED POLYMER DSM IP Assets B.V. (NL) 2005-06-15 EP disclosed
WO-2004009655-A1 A PROCESS FOR THE PREPARATION OF A HYDROGENATED POLYMER DSM IP ASSETS B.V. (NL) 2004-01-29 WO disclosed
EP-0479083-B1 Sulphur vulcanisable rubber composition having an improved degree of vulcanisation BAYER AG (DE) 1995-11-29 EP disclosed
EP-0482470-A1 Use of half esters of maleic acid and fumaric acid and their salts for reducing the formation of nitrosamines in sulfurs vulcanization BAYER AG (DE) 1992-04-29 EP disclosed
EP-0479083-A1 Sulphur vulcanisable rubber composition having an improved degree of vulcanisation BAYER AG (DE) 1992-04-08 EP disclosed