Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.44 |
| ▸ | PTAFR | P25105 | 6/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507681 | 0.87 | GRM5 (0.43) | GRM5ALDH1A1 | |
| SCHEMBL10229387 | 0.76 | GRM5 (0.48) | GRM5 | |
| Succinic Acid SCHEMBL507211 | 0.74 | FFAR1 (0.43) | GRM5 | |
| SCHEMBL13768368 | 0.74 | PTAFR (0.43) | PTAFRNOTUMALDH1A1HPGDHSD17B10 | |
| SCHEMBL507382 | 0.74 | GRM5 (0.45) | GRM5FNTAFNTB | |
| SCHEMBL507887 | 0.70 | ESR1 (0.43) | NOTUM | |
| SCHEMBL3963048 | 0.70 | ESR1 (0.43) | GRM5ALDH1A1HPGD | |
| SCHEMBL3961806 | 0.70 | ESR2 (0.46) | GRM5 | |
| SCHEMBL10884112 | 0.69 | ADRA2A (0.65) | PTAFRNOTUMALDH1A1HPGD | |
| SCHEMBL507391 | 0.68 | ESR2 (0.42) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926712-B1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2009-07-29 | — | — | EP | disclosed |