Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 17/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062159 | 0.86 | PTGES2 (0.77) | PTGES2 | |
| SCHEMBL13639450 | 0.84 | PTGES2 (0.52) | PTGES2 | |
| SCHEMBL3779094 | 0.74 | PTGES2 (0.78) | PTGES2 | |
| SCHEMBL3782941 | 0.74 | PTGES2 (0.78) | PTGES2 | |
| SCHEMBL3782945 | 0.74 | PTGES2 (0.78) | PTGES2 | |
| SCHEMBL3779099 | 0.74 | PTGES2 (0.78) | PTGES2 | |
| SCHEMBL3785279 | 0.73 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3785282 | 0.73 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3782510 | 0.73 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3775127 | 0.73 | PTGES2 (0.75) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082347-A1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |