Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964060 | 0.86 | NAMPT (0.43) | GNAI3GNAO1GNAI1NAMPTNAAA | |
| SCHEMBL3965756 | 0.85 | NAMPT (0.42) | GNAI3GNAO1GNAI1NAMPTNAAA | |
| SCHEMBL14115859 | 0.81 | NAMPT (0.40) | GNAI3GNAO1GNAI1NAMPTNAAA | |
| SCHEMBL14115777 | 0.77 | HTR2A (0.42) | HTR2AHTR2CHTR2BTP53HTT | |
| SCHEMBL13768382 | 0.72 | HTR2A (0.43) | HTR2AHTR2CHTR2BOPRM1 | |
| SCHEMBL13768681 | 0.70 | NAMPT (0.38) | GNAI3GNAO1GNAI1NAMPTNAAA | |
| SCHEMBL3961017 | 0.70 | NAMPT (0.38) | GNAI3GNAO1GNAI1NAMPTNAAA | |
| SCHEMBL3961020 | 0.70 | NAMPT (0.38) | GNAI3GNAO1GNAI1NAMPTNAAA | |
| SCHEMBL3966199 | 0.69 | NAMPT (0.37) | GNAI3GNAO1GNAI1NAMPTNAAA | |
| SCHEMBL14601593 | 0.69 | NAMPT (0.46) | NAMPTNAAAMTNR1ACNR1MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926712-B1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2009-07-29 | — | — | EP | disclosed |