Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965006 | 0.87 | NPC1 (0.42) | NAMPTDRD2DRD3CNR1 | |
| SCHEMBL14115682 | 0.85 | NAMPT (0.40) | NAMPTDRD2DRD3CNR1MTNR1A | |
| SCHEMBL3964060 | 0.83 | NAMPT (0.43) | NAMPTCNR1NAAAMTNR1AMTNR1B | |
| SCHEMBL3965756 | 0.82 | NAMPT (0.42) | NAMPTCNR1NAAAMTNR1AMTNR1B | |
| SCHEMBL14601596 | 0.81 | NAMPT (0.40) | NAMPTDRD2DRD3MTNR1AMTNR1B | |
| SCHEMBL14115859 | 0.79 | NAMPT (0.40) | NAMPTCNR1NAAAMTNR1AMTNR1B | |
| SCHEMBL13748572 | 0.74 | PNMT (0.41) | — | |
| SCHEMBL14115777 | 0.74 | HTR2A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL3970338 | 0.70 | NAMPT (0.38) | NAMPTDRD2DRD3CNR1MTNR1A | |
| SCHEMBL14091686 | 0.70 | NAMPT (0.38) | NAMPTDRD2DRD3CNR1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028131-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[d]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |