Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21698694 | 0.91 | CCNC (0.45) | HRH3CHRNB2CHRNA4CCNCCDK8 | |
| SCHEMBL18291319 | 0.89 | MAPT (0.48) | CHRNB2CHRNA4MAPTGCKCHRNB4 | |
| SCHEMBL619825 | 0.84 | MAPT (0.49) | CHRNB2CHRNA4MAPTPTPN11GCK | |
| SCHEMBL2824069 | 0.84 | USP2 (0.46) | MEN1TSHRKMT2ACHRNB2CHRNA4 | |
| SCHEMBL29891246 | 0.84 | MAPT (0.49) | CHRNB2CHRNA4MAPTPTPN11GCK | |
| SCHEMBL20037704 | 0.82 | CHRNB2 (0.40) | HRH3CHRNB2CHRNA4MAPTCCNC | |
| SCHEMBL2687238 | 0.82 | ACVR1 (0.44) | HRH3HTR3EMEN1HTR3BCYP1A2 | |
| SCHEMBL23634070 | 0.81 | PIK3CA (0.43) | HRH3CHRNB2CHRNA4MAPTGCK | |
| SCHEMBL30664069 | 0.81 | PIK3CA (0.51) | CHRNB2CHRNA4MAPTGCK | |
| SCHEMBL21245620 | 0.81 | PIK3CA (0.51) | CHRNB2CHRNA4MAPTGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085185-A1 | FUSED PYRIDINE, PYRIMIDINE AND TRIAZINE COMPOUNDS AS CELL CYCLE INHIBITORS | AMGEN INC. (US) | 2009-07-09 | — | — | WO | disclosed |