Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 14/20 | 0.77 |
| ▸ | AR | P10275 | 14/20 | 0.77 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12998927 | 1.00 | PGR (0.77) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12998934 | 0.91 | PGR (0.64) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12942949 | 0.90 | PGR (0.62) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12943028 | 0.89 | PGR (0.61) | PGRARNR3C2LMNANR3C1 | |
| SCHEMBL12943045 | 0.87 | PGR (1.00) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12998959 | 0.87 | PGR (1.00) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16572801 | 0.87 | PGR (1.00) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12942744 | 0.86 | AR (0.60) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12942788 | 0.86 | AR (0.60) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12998926 | 0.82 | PGR (0.74) | PGRARNR3C2LMNANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083272-A2 | 19-NOR-STEROID DERIVATIVES WITH A 15α,16α-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |