Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277984 | 0.93 | MAPK1 (0.35) | MAPK1SELPTYRO3DRD2DRD3 | |
| SCHEMBL1277981 | 0.93 | MAPK1 (0.35) | MAPK1SELPTYRO3DRD2DRD3 | |
| SCHEMBL1278329 | 0.90 | BTK (0.34) | MAPK1SELPTYRO3DRD2DRD3 | |
| SCHEMBL1278328 | 0.90 | BTK (0.34) | MAPK1SELPTYRO3DRD2DRD3 | |
| SCHEMBL3416958 | 0.89 | OPRM1 (0.32) | — | |
| SCHEMBL3416955 | 0.89 | OPRM1 (0.32) | — | |
| SCHEMBL1277646 | 0.88 | PDCD1 (0.33) | — | |
| SCHEMBL1277645 | 0.88 | PDCD1 (0.33) | — | |
| SCHEMBL1278178 | 0.87 | CSF1R (0.33) | — | |
| SCHEMBL1278180 | 0.87 | CSF1R (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |