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Sugi Predict / Compounds / SCHEMBL13769157

SCHEMBL13769157

SCHEMBL13769157

CC1(C)O[C@@H]2CC3[C@@H]4CCC5=Cc6c(cnn6-c6ccc(F)cc6)C[C@]5(C)C4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 20/20 0.70
▸ PGR P06401 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12574244 1.00 NR3C1 (0.70) NR3C1PGR
SCHEMBL2019175 0.94 NR3C1 (0.64) NR3C1
SCHEMBL2016244 0.93 NR3C1 (0.63) NR3C1
SCHEMBL2022003 0.92 NR3C1 (0.62) NR3C1
SCHEMBL2018613 0.91 NR3C1 (0.58) NR3C1PGR
SCHEMBL12574242 0.90 NR3C1 (0.59) NR3C1
SCHEMBL2016328 0.90 NR3C1 (0.59) NR3C1
SCHEMBL12574265 0.88 NR3C1 (0.58) NR3C1
SCHEMBL12574270 0.88 NR3C1 (0.58) NR3C1
SCHEMBL2016820 0.88 NR3C1 (0.78) NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009082342-A1 STEROID DERIVATIVES ACTING AS GLUCOCORTICOSTEROID RECEPTOR AGONISTS ASTRAZENECA AB (SE) 2009-07-02 — — WO disclosed
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