Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4104295 | 0.89 | MEN1 (1.00) | MEN1KMT2AALDH1A1MAPK1HIF1A | |
| SCHEMBL13730228 | 0.86 | MEN1 (0.80) | MEN1KMT2AALDH1A1MAPK1HIF1A | |
| SCHEMBL4105140 | 0.86 | MEN1 (0.80) | MEN1KMT2AALDH1A1MAPK1HIF1A | |
| SCHEMBL4107398 | 0.86 | MEN1 (0.80) | MEN1KMT2AALDH1A1MAPK1HIF1A | |
| SCHEMBL4090635 | 0.86 | MEN1 (0.80) | MEN1KMT2AALDH1A1MAPK1HIF1A | |
| SCHEMBL18118625 | 0.86 | MEN1 (0.79) | MEN1KMT2AALDH1A1MAPK1HIF1A | |
| SCHEMBL14132372 | 0.84 | MEN1 (0.76) | MEN1KMT2AALDH1A1MAPK1HIF1A | |
| SCHEMBL13730214 | 0.84 | MEN1 (0.76) | MEN1KMT2AALDH1A1MAPK1HIF1A | |
| SCHEMBL13730868 | 0.84 | MEN1 (0.76) | MEN1KMT2AALDH1A1MAPK1HIF1A | |
| SCHEMBL4106565 | 0.84 | MAPK1 (0.79) | MEN1KMT2AALDH1A1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082691-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS WITH SELECTIVE ANTI-MALARIAL ACTIVITY | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2009-07-02 | — | — | WO | disclosed |