Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.40 |
| ▸ | PDE4A | P27815 | 8/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909717 | 0.92 | CHRM3 (0.43) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL276474 | 0.89 | PDE10A (0.54) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL4419009 | 0.84 | PDE10A (0.45) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL4428463 | 0.84 | PDE10A (0.45) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL14440830 | 0.84 | PDE10A (0.58) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL27869897 | 0.83 | CHRM3 (0.46) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL17841520 | 0.79 | PDE10A (0.41) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL30289573 | 0.79 | PDE10A (0.41) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL11185504 | 0.76 | PDE10A (0.42) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL14435443 | 0.76 | PDE10A (0.42) | PDE10ACHRM3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |