Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.54 |
| ▸ | AR | P10275 | 8/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089114 | 0.77 | PGR (0.57) | PGRARNR3C2CYP19A1SERPINA6 | |
| SCHEMBL4213899 | 0.75 | PGR (0.55) | PGRARNR3C2CYP19A1SERPINA6 | |
| SCHEMBL13333282 | 0.73 | PGR (0.51) | PGRARNR3C2CYP19A1SERPINA6 | |
| SCHEMBL13925594 | 0.73 | PGR (0.51) | PGRARNR3C2CYP19A1SERPINA6 | |
| SCHEMBL10089124 | 0.71 | PGR (0.70) | PGRARNR3C2CYP19A1ALDH1A1 | |
| SCHEMBL4214248 | 0.71 | PGR (0.68) | PGRARNR3C2CYP19A1ALDH1A1 | |
| SCHEMBL14009903 | 0.71 | PGR (0.57) | PGRARNR3C2CYP19A1SERPINA6 | |
| SCHEMBL10089121 | 0.71 | PGR (0.68) | PGRARNR3C2CYP19A1ALDH1A1 | |
| SCHEMBL14009969 | 0.71 | CYP19A1 (0.56) | PGRARNR3C2CYP19A1SERPINA6 | |
| SCHEMBL13796510 | 0.70 | PGR (0.47) | PGRARNR3C2CYP19A1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083270-A1 | 15,16-METHYLENE-STEROID-17,17-LACTOL DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |